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The evolving process of ferroptosis in thyroid cancer: Novel mechanisms and opportunities

1 Aug 2024

Abstract excerpt

Thyroid cancer (TC) is a prevalent endocrine malignancy, with a significant increase in incidence worldwide. Ferroptosis is a novel form of programmed cell death, primarily caused by iron overload and reactive oxygen species (ROS)-dependent accumulation of lipid peroxides. The main manifestations of cellular ferroptosis are rupture of the outer membrane, crumpling of the mitochondria and shrinkage or...

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PMID: 39163517
DOI: 10.1111/jcmm.18587

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