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Identification of the novel exhausted T cell CD8 + markers in breast cancer

19 Aug 2024

Abstract excerpt

Cancer is one of the most concerning public health issues and breast cancer is one of the most common cancers in the world. The immune cells within the tumor microenvironment regulate cancer development. In this study, single immune cell data sets were used to identify marker gene sets for exhausted CD8 + T cells (CD8Tex) in breast cancer. Machine learning methods were used to cluster subtypes and establish the...

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PMID: 39160211
DOI: 10.1038/s41598-024-70184-1

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