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Article

Adapting cytoskeleton-mitochondria patterning with myocyte differentiation by promyogenic PRR33

15 Aug 2024

Abstract excerpt

Coordinated cytoskeleton-mitochondria organization during myogenesis is crucial for muscle development and function. Our understanding of the underlying regulatory mechanisms remains inadequate. Here, we identified a novel muscle-enriched protein, PRR33, which is upregulated during myogenesis and acts as a promyogenic factor. Depletion of Prr33 in C2C12 represses myoblast differentiation. Genetic deletion of...

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PMID: 39147882
DOI: 10.1038/s41418-024-01363-w

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