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Inflammatory breast cancer microenvironment repertoire based on DNA methylation data deconvolution reveals actionable targets to enhance the treatment efficacy

5 Aug 2024

Abstract excerpt

BACKGROUND: Although the clinical signs of inflammatory breast cancer (IBC) resemble acute inflammation, the role played by infiltrating immune and stromal cells in this aggressive disease is uncharted. The tumor microenvironment (TME) presents molecular alterations, such as epimutations, prior to morphological abnormalities. These changes affect the distribution and the intricate communication between the TME...

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PMID: 39103878
DOI: 10.1186/s12967-024-05553-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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