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Association and function analysis of genetic variants and the risk of gestational diabetes mellitus in a southern Chinese population.

Frontiers in endocrinology - 1 Jan 2024

Liang Qiulian, Sun Yan, Li Ming, Li Ruiqi, Nie Lijie, Lin Lin, Yu Xiangyuan

Abstract excerpt

Background: Gestational diabetes mellitus (GDM) is a complex metabolic disease that has short-term and long-term adverse effects on mothers and infants. However, the specific pathogenic mechanism has not been elucidated. Objective: The aim of this study was to confirm the associations between candidate genetic variants (rs4134819, rs720918, rs2034410, rs11109509, and rs12524768) and GDM risk and prediction in a...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Topics

Adult
Female
Humans
Pregnancy
Case-Control Studies
China
Diabetes, Gestational
East Asian People
Genetic Predisposition to Disease
Genotype
Nomograms
Polymorphism, Single Nucleotide
Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39777224
DOI: 10.3389/fendo.2024.1476222
PMCID: PMC11703716

Genes

XAB2
CPE
TG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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