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Article

Single-cell RNA sequencing reveals placental response under environmental stress

2 Aug 2024

Abstract excerpt

The placenta is crucial for fetal development, yet the impact of environmental stressors such as arsenic exposure remains poorly understood. We apply single-cell RNA sequencing to analyze the response of the mouse placenta to arsenic, revealing cell-type-specific gene expression, function, and pathological changes. Notably, the Prap1 gene, which encodes proline-rich acidic protein 1 (PRAP1), is significantly...

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PMID: 39095385
DOI: 10.1038/s41467-024-50914-9

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