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Analysis of sputum microbial metagenome in COPD based on exacerbation frequency and lung function: a case control study

19 Nov 2022

Abstract excerpt

Abstract Background The role of the sputum microbiome in chronic obstructive pulmonary disease (COPD) progression remains elusive. As the advent of the new culture-independent microbial sequencing technique makes it possible to disclose the complex microbiome community of the respiratory tract. The aim of this study was to use metagenomic next-generation sequencing (mNGS) to confirm whether there are differences...

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PMID: 36403054
DOI: 10.1186/s12931-022-02246-9

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