Article
Microaerobic-mediated suppression of Klebsiella pneumoniae mucoviscosity is restored by rmpD overexpression.
Journal of applied microbiology - 5 Aug 2024
Sun Wangnan, Rong Chengbo, Chen Liang, Li Jiarui, An Zhijing, Yue Jinglin, Wei Hengkun, Han Kai, Hua Mingxi, Zeng Hui, Chen Chen
Abstract excerpt
AIMS: Hypervirulent Klebsiella pneumoniae (hvKp) causes invasive community-acquired infections in healthy individuals, and hypermucoviscosity (HMV) is the main phenotype associated with hvKp. This study investigates the impact of microaerobic environment availability on the mucoviscosity of K. pneumoniae. METHODS AND RESULTS: By culturing 25 clinical strains under microaerobic and aerobic environments, we...
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