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Article

Circulating immune cells and risk of osteosarcoma: a Mendelian randomization analysis.

Frontiers in immunology - 1 Jan 2024

Li Lan, Sun Yeqi, Luo Jia, Liu Mengjiao

Abstract excerpt

Objectives: Osteosarcoma (OS) is the primary bone tumor originating from transformed mesenchymal cells. It is unclear whether associations between specific circulating immune cells and OS are causal or due to bias. To clarify whether predicted genetically altered circulating immune cells are associated with OS development, we performed a two-sample Mendelian randomization (MR) analysis. Methods: The genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39081321
DOI: 10.3389/fimmu.2024.1381212
PMCID: PMC11286390

Genes

CD28
CD4
CD80
CD24
CD27
CD38

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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