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Antigenic cartography using variant-specific hamster sera reveals substantial antigenic variation among Omicron subvariants

30 Jul 2024

Abstract excerpt

Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) has developed substantial antigenic variability. As the majority of the population now has pre-existing immunity due to infection or vaccination, the use of experimentally generated animal immune sera can be valuable for measuring antigenic differences between virus variants. Here, we immunized Syrian hamsters by two successive infections with one of...

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PMID: 39078681
DOI: 10.1073/pnas.2310917121

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