Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) - 1 Sept 2024

Wang Jiqun, Liu Wenwen, Huang Yunyuan, Wang Guangwei, Guo Xiaobo, Shi Donglei, Sun Tianyue, Xiao Chaojiang, Zhang Chao, Jiang Bei, Guo Yuan, Li Jian

Abstract excerpt

The pursuit of pharmacological interventions in aging aims focuses on maximizing safety and efficacy, prompting an exploration of natural products endowed with inherent medicinal properties. Subsequently, this work establishes a unique library of plant extracts sourced from Yunnan Province, China. Screening of this herbal library herein revealed that Salsola collina (JM10001) notably enhances both lifespan and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Models, Animal

Share to Longevity

Share to Phenotype

Share to Plant Extracts

Source

Open in PubMed Open full text

Identifiers

PMID: 39073681
DOI: 10.1002/advs.202401862
PMCID: PMC11423240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Senomorphlytic Three-Drug Combination Discovered in Salsola collina for Delaying Aging Phenotypes and Extending Healthspan.PMID 39073681Read ↗

Nicandra physalodes Extract Exerts Antiaging Effects in Multiple Models and Extends the Lifespan of Caenorhabditis elegans via DAF‐16 and HSF‐1Semantic proximity Read ↗

Senolytics and senomorphics: Natural and synthetic therapeutics in the treatment of aging and chronic diseasesSemantic proximity Read ↗

Natural compounds with anti-ageing activitySemantic proximity Read ↗

Development of novel flavonoid senolytics through phenotypic drug screening and drug designSemantic proximity Read ↗

Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathwaySemantic proximity Read ↗

Finding Ponce de Leon’s Pill: Challenges in Screening for Anti-Aging MoleculesSemantic proximity Read ↗

Current Perspective in the Discovery of Anti-aging Agents from Natural ProductsSemantic proximity Read ↗

Emerging use of senolytics and senomorphics against aging and chronic diseasesSemantic proximity Read ↗

Quantitative and Systems Pharmacology 3. Network-Based Identification of New Targets for Natural Products Enables Potential Uses in Aging-Associated DisordersSemantic proximity Read ↗

Repurposing the plant-derived compound apigenin for senomorphic effect in antiaging pipelinesSemantic proximity Read ↗

Anti-aging effects of dietary phytochemicals: From Caenorhabditis elegans , Drosophila melanogaster , rodents to clinical studiesSemantic proximity Read ↗

Phenolic monoterpene Bakuchiol ameliorates age related ParkinsonismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.