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Article

Nuclear pyruvate dehydrogenase complex regulates histone acetylation and transcriptional regulation in the ethylene response.

Science advances - 26 Jul 2024

Shao Zhengyao, Bian Liangqiao, Ahmadi Shyon K, Daniel Tyler J, Belmonte Miguel A, Burns Jackson G, Kotla Prashanth, Bi Yang, Shen Zhouxin, Xu Shou-Ling, Wang Zhi-Yong, Briggs Steven P, Qiao Hong

Abstract excerpt

Ethylene plays its essential roles in plant development, growth, and defense responses by controlling the transcriptional reprograming, in which EIN2-C-directed regulation of histone acetylation is the first key step for chromatin to perceive ethylene signaling. But how the nuclear acetyl coenzyme A (acetyl CoA) is produced to ensure the ethylene-mediated histone acetylation is unknown. Here we report that...

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Identifiers

PMID: 39058774
DOI: 10.1126/sciadv.ado2825
PMCID: PMC11277378

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