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Multilocus sequence typing database for Streptococcus agalactiae contains a spurious allele of the transketolase gene.

Microbiology spectrum - 3 Sept 2024

Chen Swaine L, Tiruvayipati Suma, Tang Wen Ying, M S Barkham Timothy

Abstract excerpt

The tkt (transketolase) gene is one of the seven gene fragments used in the multilocus sequence typing (MLST) system for Streptococcus agalactiae. We discovered that the tkt_134 allele is derived from a homologous gene (which we designate tktX) that is not present in all S. agalactiae; all known strains that contain a match to the tkt_134 allele also contain a gene sequence that is much closer in sequence...

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Identifiers

PMID: 39052441
DOI: 10.1128/spectrum.00537-24
PMCID: PMC11370237

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