Article
Histogenetic insights and genetic landscape of fibromatosis-like undifferentiated gastric carcinoma: a focused study.
World journal of surgical oncology - 24 Jul 2024
Wang Yang-Kun, Wang Su-Nan, Liao Xing-Hai, Wang Zhi-Qiang, Li Ping, Yun Tian, Meng De-Qi
Abstract excerpt
BACKGROUND: The aim of this study was to elucidate the histogenesis and genetic underpinnings of fibromatosis-like undifferentiated gastric carcinoma (FLUGC), a rare pathological entity. METHOD: Through a detailed analysis of seven cases, including histopathological evaluation, CTNNB1 gene mutation screening, human epidermal growth factor receptor 2 (HER2) protein level quantification, and HER2 gene amplification...
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