Article
Changes in Mutations of Cell-Free DNA and Liver Tumor Tissue in Patients with Advanced Hepatocellular Carcinoma before and after Introduction of Lenvatinib.
Oncology - 1 Jan 2024
Tsuruoka Mio, Ninomiya Masashi, Inoue Jun, Iwata Tomoaki, Sano Akitoshi, Sato Kosuke, Onuki Masazumi, Sawahashi Satoko, Masamune Atsushi
Abstract excerpt
INTRODUCTION: Cell-free DNA (cfDNA) is expected to contribute to the decision for treatment and prediction of effects with minimally invasion. We investigated the correlation between gene mutations before and after lenvatinib (LEN) treatment and its effectiveness, in order to find advanced hepatocellular carcinoma (HCC) patients who would benefit greatly from the therapy. METHODS: We analyzed cfDNA before and 6-8...
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