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Gestational exposure to air pollutants perturbs metabolic and placenta-fetal phenotype.

Reproductive toxicology (Elmsford, N.Y.) - 1 Sept 2024

Ganguly Amit, Ghosh Shubhamoy, Shin Bo-Chul, Touma Marlin, Wadehra Madhuri, Devaskar Sherin U

Abstract excerpt

Air pollution (AP) is detrimental to pregnancies including increasing risk factors of gestational diabetes mellitus. We hypothesized that exposure to AP causes cardiovascular and metabolic disruption thereby altering placental gene expression, which in turn affects the placental phenotype and thereby embryonic/fetal development. To test this hypothesis, we investigated the impact of intra-nasal instilled AP upon...

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PMID: 39002939
DOI: 10.1016/j.reprotox.2024.108657

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