Article
Comparative pathogenesis of three Mayaro virus genotypes in the cynomolgus macaque.
The Journal of general virology - 1 Jul 2024
Hamilton Melissa M, Webb Emily M, Peterson Max C, Patel Grishma, Porto Maciel, Orekov Tatyana, Erasmus Jesse H, Finneyfrock Brad, Cook Anthony, Auguste Albert J, Kar Swagata
Abstract excerpt
Mayaro virus (MAYV), a mosquito-borne alphavirus, is considered an emerging threat to public health with epidemic potential. Phylogenetic studies show the existence of three MAYV genotypes. In this study, we provide a preliminary analysis of the pathogenesis of all three MAYV genotypes in cynomolgus macaques (Macaca facicularis, Mauritian origin). Significant MAYV-specific RNAemia and viremia were detected during...
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