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Article

Inflammatory Giant Cell Carcinoma of the Lung: Clinicopathologic, Immunohistochemical, and Next-generation Sequencing Study of 14 Cases.

The American journal of surgical pathology - 1 Oct 2024

Suster David I, Mackinnon A Craig, Ronen Natali, Mejbel Haider A, Harada Shuko, Michal Michael, Suster Saul

Abstract excerpt

A distinctive histological variant of poorly differentiated, sarcomatoid, non-small cell lung carcinoma characterized by a discohesive population of giant tumor cells associated with prominent interstitial inflammatory cell infiltrates is described. The tumors occurred in 7 women and 7 men, 42 to 72 years of age (mean: 56 y). They predominantly affected the upper lobes and measured 1.3 to 9 cm in greatest...

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PMID: 38989701
DOI: 10.1097/PAS.0000000000002285

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