Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SEC61 translocon gamma subunit is correlated with glycolytic activity, epithelial mesenchymal transition and the immune suppressive phenotype of lung adenocarcinoma.

Acta biochimica et biophysica Sinica - 8 Jul 2024

Zhou Changshuai, Cui Huanhuan, Yang Yuechao, Chen Lei, Feng Mingtao, Gao Yang, Li Deheng, Li Liangdong, Chen Xin, Li Xiaoqiu, Cao Yiqun

Abstract excerpt

Lung adenocarcinoma (LUAD) remains a predominant cause of cancer-related mortality globally, underscoring the urgency for targeted therapeutic strategies. The specific role and impact of the SEC61 translocon gamma subunit (SEC61G) in LUAD progression and metastasis remain largely unexplored. In this study, we use a multifaceted approach, combining bioinformatics analysis with experimental validation, to elucidate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to A549 Cells
Share to Adenocarcinoma of Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Epithelial-Mesenchymal Transition

Share to Gene Expression Regulation, Neoplastic

Share to Glycolysis

Share to SEC Translocation Channels

Share to Tumor Microenvironment

Source

Open in PubMed Open full text

Identifiers

PMID: 38978503
DOI: 10.3724/abbs.2024109
PMCID: PMC11693863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SEC61 translocon gamma subunit is correlated with glycolytic activity, epithelial mesenchymal transition and the immune suppressive phenotype of lung adenocarcinoma.PMID 38978503Read ↗

Prognostic value of SEC61G in lung adenocarcinoma: a comprehensive study based on bioinformatics and in vitro validationSemantic proximity Read ↗

SEC61G Overexpression and DNA Amplification Correlates With Prognosis and Immune Cell Infiltration in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

SEC61G regulates breast cancer cell proliferation and metastasis by affecting the Epithelial-Mesenchymal TransitionSemantic proximity Read ↗

SEC61G assists EGFR -amplified glioblastoma to evade immune eliminationSemantic proximity Read ↗

GNG7 as a tumor-suppressor gene in lung adenocarcinoma: implications for prognosis and immune-based therapiesSemantic proximity Read ↗

SEC61G Overexpression and DNA Amplification Correlates With Prognosis and Immune Cell Infiltration in Head and Neck Squamous Cell CarcinomaSemantic proximity Read ↗

Pan-cancer analysis identifies SEC11A as an immunological and prognostic biomarkerSemantic proximity Read ↗

Glut10 is a Novel Immune Regulator Involved in Lung Cancer Immune Cell Infiltration and Predicts Worse Survival When Transcriptionally Down-RegulatedSemantic proximity Read ↗

B3GNT3 as a prognostic biomarker and correlation with immune cell infiltration in lung adenocarcinomaSemantic proximity Read ↗

Integrated proteomic and glycoproteomic analysis reveals heterogeneity and molecular signatures of brain metastases from lung adenocarcinomas.Semantic proximity Read ↗

Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapySemantic proximity Read ↗

NSUN2 Promotes Cancer Immune Evasion via Its Moonlighting Function Acting on Metabolic Reprogramming.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.