Article
Application prospects of the 2BS cell-adapted China fixed rabies virus vaccine strain 2aG4-B40.
Virology journal - 8 Jul 2024
Xu Ying, Weng Lin, Wang Xuan, Li Ming, Guo Wanping, Liu Yiqing, Li Xiang, Wang Zhenping, Liu Xinyu, Xu Shengnan, He Feide, Hou Qianqian, Li Tengzhou, Du Wenke, Zhang Yabo, Chang Shumin, Zhang Liwen, Zhang Yuntao
Abstract excerpt
BACKGROUND: Rabies is a fatal zoonotic disease whose pathogenesis has not been fully elucidated, and vaccination is the only effective method for protecting against rabies virus infection. Most inactivated vaccines are produced using Vero cells, which are African green monkey kidney cells, to achieve large-scale production. However, there is a potential carcinogenic risk due to nonhuman DNA contamination. Thus,...
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