Article
Characterization of senescent mesenchymal stem/stromal cells derived from equine bone marrow and the effects of NANOG on the senescent phenotypes.
The Journal of veterinary medical science - 1 Sept 2024
Kushida Chiho, Tamura Norihisa, Kasashima Yoshinori, Sato Kota, Arai Katsuhiko
Abstract excerpt
In equine regenerative medicine using bone marrow-derived mesenchymal stem/stromal cells (BM-MSC), the importance of the quality management of BM-MSC has been widely recognized. However, there is little information concerning the relationship between cellular senescence and the stemness in equine BM-MSC. In this study, we showed that stemness markers (NANOG, OCT4, SOX2 and telomerase reverse transcriptase) and...
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