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Article

Single nucleotide polymorphisms of GEMIN3 modify the risk of primary Sjögren's syndrome in female patients.

The American journal of the medical sciences - 1 Feb 2025

Wang Dong, Zhang Jingjing, Zhao Yufei, Cao Ruijie, Wang Yingnan, Guo Iren, Peng Chenxing, Song Yanrong, Zhang Shasha

Abstract excerpt

BACKGROUND: MicroRNA (miRNA)-processing machinery may modify the risk of primary Sjögren's syndrome (pSS) by altering miRNA expression profiles. Inflammatory cytokines and reactive oxygen species (ROS) are also involved in pSS; however, the role of altered miRNAs expression in its pathogenesis is still unclear. We aimed to evaluate the relationship between single-nucleotide polymorphisms (SNPs) in miRNA...

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Source

Identifiers

PMID: 38969288
DOI: 10.1016/j.amjms.2024.07.001

Genes

TNF
GEMIN4
RAN
XPO5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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