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Alterations of the bile microbiome is associated with progression-free survival in pancreatic ductal adenocarcinoma patients

1 Jul 2024

Abstract excerpt

BACKGROUND: Patients with pancreatic ductal adenocarcinoma (PDAC) display an altered oral, gastrointestinal, and intra-pancreatic microbiome compared to healthy individuals. However, knowledge regarding the bile microbiome and its potential impact on progression-free survival in PDACs remains limited. METHODS: Patients with PDAC (n = 45), including 20 matched pairs before and after surgery, and benign controls (n...

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PMID: 38956452
DOI: 10.1186/s12866-024-03371-9

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