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Article

Six adenoviral vectored African swine fever virus genes protect against fatal disease caused by genotype I challenge.

Journal of virology - 23 Jul 2024

Portugal Raquel, Goldswain Hannah, Moore Rebecca, Tully Matthew, Harris Katie, Corla Amanda, Flannery John, Dixon Linda K, Netherton Christopher L

Abstract excerpt

African swine fever virus causes a lethal hemorrhagic disease in domestic swine and wild boar for which currently licensed commercial vaccines are only available in Vietnam. Development of subunit vaccines is complicated by the lack of information on protective antigens as well as suitable delivery systems. Our previous work showed that a pool of eight African swine fever virus genes vectored using an adenovirus...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38953377
DOI: 10.1128/jvi.00622-24
PMCID: PMC11264932

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