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Investigation of RBM10 mutation and its associations with clinical and molecular characteristics in EGFR-mutant and EGFR-wildtype lung adenocarcinoma

31 May 2024

Abstract excerpt

Background RBM10 is commonly mutated in lung adenocarcinoma (LUAD). However, its role in the pathogenesis of LUAD remains undefined. EGFR -mutant LUAD represents a distinct subset of non-small cell lung cancer (NSCLC). The function of RBM10 in tumor pathogenesis is supposed to differ between EGFR -mutant and EGFR -wt LUAD. This study aimed to interrogate the prevalence of RBM10 mutation in a large cohort of...

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PMID: 38912481
DOI: 10.1016/j.heliyon.2024.e32287

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