Article
Ethanol-induced genotoxicity.
Mutation research - 1 Jan 2000
Hayes S
Abstract excerpt
Unrelated, nondenatured, ethanol preparations, derived synthetically or by fermentation, were found to induce qualitatively similar concentration-dependent toxic and genotoxic effects as measured by RK mutatest. In this system ethanol was found genotoxic above a threshold concentration of 18-19% (v/v) when RK+ selector cells were transiently exposed for 10 min before selection for RK- survivors at 42 degrees C.
Topics
- Dose-Response Relationship, Drug
- Escherichia coli
- Ethanol
- Mutagenicity Tests
- Mutation