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Genome-Wide Admixture and Association Study of Serum Selenium Deficiency to Identify Genetic Variants Indirectly Linked to Selenium Regulation in Brazilian Adults.

Nutrients - 26 May 2024

Moriguchi Watanabe Ligia, Sousa Lisete, Couto Francisco M, Noronha Natália Yumi, de Souza Pinhel Marcela Augusta, da Silva Carvalho Gleyson Francisco, da Silva Rodrigues Guilherme, Bueno Júnior Carlos Roberto, Kulikowski Leslie Domenici, Barbosa Júnior Fernando, Nonino Carla Barbosa

Abstract excerpt

Blood selenium (Se) concentrations differ substantially by population and could be influenced by genetic variants, increasing Se deficiency-related diseases. We conducted a genome-wide association study (GWAS) to identify single nucleotide polymorphisms (SNPs) associated with serum Se deficiency in 382 adults with admixed ancestry. Genotyping arrays were combined to yield 90,937 SNPs. R packages were applied to...

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Identifiers

PMID: 38892560
DOI: 10.3390/nu16111627
PMCID: PMC11175099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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