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Article

Left ventricular trabeculation in Hominidae: divergence of the human cardiac phenotype.

Communications biology - 14 Jun 2024

Curry Bryony A, Drane Aimee L, Atencia Rebeca, Feltrer Yedra, Calvi Thalita, Milnes Ellie L, Moittié Sophie, Weigold Annika, Knauf-Witzens Tobias, Sawung Kusuma Arga, Howatson Glyn, Palmer Christopher, Stembridge Mike R, Gorzynski John E, Eves Neil D, Dawkins Tony G, Shave Rob E

Abstract excerpt

Although the gross morphology of the heart is conserved across mammals, subtle interspecific variations exist in the cardiac phenotype, which may reflect evolutionary divergence among closely-related species. Here, we compare the left ventricle (LV) across all extant members of the Hominidae taxon, using 2D echocardiography, to gain insight into the evolution of the human heart. We present compelling evidence...

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PMID: 38877299
DOI: 10.1038/s42003-024-06280-9
PMCID: PMC11178792

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