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Ergone Derivatives from the Deep-Sea-Derived Fungus Aspergillus terreus YPGA10 and 25,28-Dihydroxyergone-Induced Apoptosis in Human Colon Cancer SW620 Cells

10 Jun 2024

Abstract excerpt

Ten new ergone derivatives ( 1 – 10 ) and five known analogues ( 11 – 15 ) were isolated from the deep-sea-derived fungus Aspergillus terreus YPGA10. The structures including the absolute configurations were established by detailed analysis of the NMR spectroscopic data, HRESIMS, ECD calculation, and coupling constant calculation. All the structures are characterized by a highly conjugated...

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PMID: 38856635
DOI: 10.1021/acs.jnatprod.4c00154

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