Antibacterial oxygenated ergostane-type steroids produced by the marine sponge-derived fungus Aspergillus sp.

Abstract excerpt

Two oxygenated ergostane-type steroids including one new compound, 3β-hydroxy-5α,6β-methoxyergosta-7,22-dien-15-one (1) along with a known analogue ergosta-6,22-dien-3β,5α,8α-triol (2) were isolated from the crude extracts of the marine sponge-derived fungus Aspergillus sp. Their structures were elucidated on the basis of combined NMR and MS spectroscopic methods. Compound 1 was a marine ergostane-type steroid...

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