Article
Biologically meaningful genome interpretation models to address data underdetermination for the leaf and seed ionome prediction in Arabidopsis thaliana.
Scientific reports - 8 Jun 2024
Raimondi Daniele, Passemiers Antoine, Verplaetse Nora, Corso Massimiliano, Ferrero-Serrano Ángel, Nazzicari Nelson, Biscarini Filippo, Fariselli Piero, Moreau Yves
Abstract excerpt
Genome interpretation (GI) encompasses the computational attempts to model the relationship between genotype and phenotype with the goal of understanding how the first leads to the second. While traditional approaches have focused on sub-problems such as predicting the effect of single nucleotide variants or finding genetic associations, recent advances in neural networks (NNs) have made it possible to develop...
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