Article
Longitudinal patient-reported outcomes on genotype-guided irinotecan dosing: feasibility and clinical relevance.
The oncologist - 6 Sept 2024
Sorah Jonathan D, Deal Allison M, Stein Sophia I, Jonsson Mattias, Innocenti Federico, Turk Anita, Boles Jeremiah C, Irvin William, Basch Ethan M, Sanoff Hanna K, Wood William A
Abstract excerpt
INTRODUCTION: Standard investigator-based adverse events (AE) assessment is via CTCAE for clinical trials. However, including the patient perspective through PRO (patient-reported outcomes) enhances clinicians' understanding of patient toxicity and fosters early detection of AEs. We assessed longitudinal integration of PRO-CTCAE within clinical workflow in a phase II trial. MATERIALS AND METHODS: As a sub-study...
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