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Article

Mutational landscape of HSP family on human breast cancer.

Scientific reports - 30 May 2024

Fernandez-Muñoz Juan Manuel, Guerrero-Gimenez Martin Eduardo, Ciocca Leonardo Andrés, Germanó María José, Zoppino Felipe Carlos Martin

Abstract excerpt

Breast cancer (BRCA) is a prevalent malignancy with the highest incidence among females. BRCA can be categorized into five intrinsic molecular subtypes (LumA, LumB, HER2, Basal, and Normal), each characterized by varying molecular and clinical features determined by the expression of intrinsic genes (PAM50). The Heat Shock Protein (HSP) family is composed of 95 genes evolutionary conservated, they have critical...

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Identifiers

PMID: 38816397
DOI: 10.1038/s41598-024-61807-8
PMCID: PMC11139924

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