Article
7 Tesla magnetic resonance spectroscopic imaging predicting IDH status and glioma grading.
Cancer imaging : the official publication of the International Cancer Imaging Society - 27 May 2024
Cadrien Cornelius, Sharma Sukrit, Lazen Philipp, Licandro Roxane, Furtner Julia, Lipka Alexandra, Niess Eva, Hingerl Lukas, Motyka Stanislav, Gruber Stephan, Strasser Bernhard, Kiesel Barbara, Mischkulnig Mario, Preusser Matthias, Roetzer-Pejrimovsky Thomas, Wöhrer Adelheid, Weber Michael, Dorfer Christian, Trattnig Siegfried, Rössler Karl, Bogner Wolfgang, Widhalm Georg, Hangel Gilbert
Abstract excerpt
INTRODUCTION: With the application of high-resolution 3D 7 Tesla Magnetic Resonance Spectroscopy Imaging (MRSI) in high-grade gliomas, we previously identified intratumoral metabolic heterogeneities. In this study, we evaluated the potential of 3D 7 T-MRSI for the preoperative noninvasive classification of glioma grade and isocitrate dehydrogenase (IDH) status. We demonstrated that IDH mutation and glioma grade...
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