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Article

Epigenome–metabolism nexus in the retina: implications for aging and disease

22 May 2024

Abstract excerpt

Intimate links between epigenome modifications and metabolites allude to a crucial role of cellular metabolism in transcriptional regulation. Retina, being a highly metabolic tissue, adapts by integrating inputs from genetic, epigenetic, and extracellular signals. Precise global epigenomic signatures guide development and homeostasis of the intricate retinal structure and function. Epigenomic and metabolic...

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PMID: 38782642
DOI: 10.1016/j.tig.2024.04.012

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