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Molecular dissection of the pseudokinase ZED1 expands effector recognition to the tomato immune receptor ZAR1.

Plant physiology - 2 Sept 2024

Diplock Nathan, Baudin Maël, Xiang Xincheng Derek, Liang Lung-Yu, Dai Weiwen, Murphy James M, Lucet Isabelle S, Hassan Jana A, Lewis Jennifer D

Abstract excerpt

The highly conserved angiosperm immune receptor HOPZ-ACTIVATED RESISTANCE 1 (ZAR1) is a bacterial pathogen recognition hub that mediates resistance by guarding host kinases for modification by pathogen effectors. The pseudokinase HOPZ-ETI DEFICIENT 1 (ZED1) is the only known ZAR1-guarded protein that interacts directly with a pathogen effector, HopZ1a, from the bacterial pathogen Pseudomonas syringae, making it a...

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PMID: 38748589
DOI: 10.1093/plphys/kiae268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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