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Article

The landscape of genetic variations in non-syndromic primary ovarian insufficiency in the MENA region: a systematic review.

Frontiers in endocrinology - 1 Jan 2023

Allouch Asma, Al-Barazenji Tara, Al-Shafai Mashael, Abdallah Atiyeh M

Abstract excerpt

Introduction: Premature ovarian insufficiency (POI) is a primary cause of infertility with variable clinical manifestations. POI is a multifactorial disease with both environmental and known genetic etiologies, but data on the genetic variations associated with POI in the Middle East and North Africa (MENA) region are scarce. The aim of this study was to systematically review all known genetic causes of POI in...

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Identifiers

PMID: 38737775
DOI: 10.3389/fendo.2023.1289333
PMCID: PMC11082268

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