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Multi-omics integration highlights the role of ubiquitination in endometriosis fibrosis

12 May 2024

Abstract excerpt

BACKGROUND: Endometriosis, characterized by the presence of active endometrial-like tissues outside the uterus, causes symptoms like dysmenorrhea and infertility due to the fibrosis of endometrial cells, which involves excessive deposition of extracellular matrix (ECM) proteins. Ubiquitination, an important post-transcriptional modification, regulates various biological processes in human diseases. However, its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38735939
DOI: 10.1186/s12967-024-05245-0

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