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Article

Evaluating possible maternal effect lethality and genetic background effects in Naa10 knockout mice.

PloS one - 1 Jan 2024

Lyon Gholson J, Longo Joseph, Garcia Andrew, Inusa Fatima, Marchi Elaine, Shi Daniel, Dörfel Max, Arnesen Thomas, Aldabe Rafael, Lyons Scott, Nashat Melissa A, Bolton David

Abstract excerpt

Amino-terminal (Nt-) acetylation (NTA) is a common protein modification, affecting approximately 80% of all human proteins. The human essential X-linked gene, NAA10, encodes for the enzyme NAA10, which is the catalytic subunit in the N-terminal acetyltransferase A (NatA) complex. There is extensive genetic variation in humans with missense, splice-site, and C-terminal frameshift variants in NAA10. In mice, Naa10...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38713657
DOI: 10.1371/journal.pone.0301328
PMCID: PMC11075865

Genes

NAA10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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