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Putative extensive and pre-extensive drug resistant-tuberculosis associated with unusual genotypes on the Thailand-Myanmar border.

Revista do Instituto de Medicina Tropical de Sao Paulo - 1 Jan 2021

Rudeeaneksin Janisara, Klayut Wiphat, Srisungngam Sopa, Bunchoo Supranee, Toonkomdang Sarawut, Wongchai Thanee, Chuenchom Nattagarn, Phetsuksiri Benjawan

Abstract excerpt

Extensive drug-resistant tuberculosis (XDR-TB) is highly life threatening and its diagnosis is usually difficult and time-consuming. Here we present the first two cases of XDR and pre-XDR-TB diagnosed in 2018 on the Thailand-Myanmar border, more specifically in Tak province. Rapid detection of XDR-TB was performed by loop-mediated isothermal amplification (LAMP), Xpert MTB/RIF, and line probe assays. Mutation...

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Identifiers

PMID: 34878043
DOI: 10.1590/S1678-9946202163085
PMCID: PMC8660029

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