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Article

Molecular investigations on T cell subsets in patients affected by hypomorphic DCLRE1C mutation.

Expert review of clinical immunology - 1 Mar 2025

Karaselek Mehmet Ali, Duran Tugce, Kuccukturk Serkan, Hazar Esra, Dogar Oznur, Kıykım Ayca, Guner Sukru, Reisli Ismail, Keles Sevgi

Abstract excerpt

OBJECTIVE: In this study, we explored the expression of transcription factors, cytokines, and co-stimulatory molecules within the helper T (Th) cell subsets (Th1, Th2, Th17, and Treg) of patients with hypomorphic DCLRE1C gene mutations. METHODS: The study comprised eight patients and five controls. Transcription factor and cytokine expressions of Th subsets and co-stimulatory molecules were investigated by qPCR...

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Source

Identifiers

PMID: 38706114
DOI: 10.1080/1744666X.2024.2352479

Genes

DCLRE1C

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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