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Mild cognitive impairment among LRRK2 and GBA1 patients with Parkinson's disease.

Parkinsonism & related disorders - 1 Jun 2024

Thaler Avner, Livne Vered, Rubinstein Einat, Omer Nurit, Faust-Socher Achinoam, Cohen Batsheva, Giladi Nir, Shirvan Julia C, Cedarbaum Jesse M, Gana-Weisz Mali, Goldstein Orly, Orr-Urtreger Avi, Alcalay Roy N, Mirelman Anat

Abstract excerpt

BACKGROUND: Mild cognitive impairment (MCI) is common in Parkinson's disease (PD). We aimed to assess the incidence of MCI among patients with PD, carriers of mutations in LRRK2 and GBA1 genes, based on the movement disorder society (MDS) criteria for the diagnosis of MCI in early-stage PD. METHODS: Patients with PD were included if they scored ≤2 on the Hoehn and Yahr and ≤6 years since motor symptom onset. A...

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PMID: 38691978
DOI: 10.1016/j.parkreldis.2024.106970

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