Article
Roles of blood metabolites in mediating the relationship between vitiligo and autoimmune diseases: Evidence from a Mendelian randomization study.
International immunopharmacology - 30 May 2024
Yang Siyu, Hu Xinglin, Zou Puyu, Zeng Zhuotong, Hu Yibo, Xiao Rong
Abstract excerpt
OBJECTIVE: This study employed Mendelian Randomization (MR) to investigate the causal relationship between genetic susceptibility to vitiligo and the risk of various autoimmune diseases, along with the mediating role of blood metabolites. METHODS: We performed two-sample MR analyses using aggregated genome-wide association studies (GWAS) data on 486 blood metabolites, vitiligo, and nine autoimmune diseases to...
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