Article
Simple, ultrasensitive detection of superoxide anion radical mutations in melanoma mice with SERS microneedles.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 5 Aug 2024
He Miao, Jin Lili, Wang Feng, Wang Xin, You Yanli, He Hongyan
Abstract excerpt
Elevated levels of superoxide anion radicals (O2·-) have been implicated in the pathogenesis of a variety of diseases, such as cancer, inflammatory diseases and autoimmune diseases. To determine the O2·- concentration for assisting disease detection, a method based on surface-enhanced Raman scattering (SERS) combined with transparent polymer microneedles has been developed. Photocrosslinked NOA61 is used to...
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