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Article

Familial Cases of Legg-Calvé-Perthes Disease-Hemostatic and Molecular Markers.

International journal of molecular sciences - 26 Feb 2026

Hernández-Zamora Edgar, Rodríguez-Olivas Armando Odiseo, Galicia-Alvarado Marlene Alejandra, Casas-Ávila Leonora, Rosales-Cruz Erika, Zavala-Hernández Cesar, Reyes-Maldonado Elba

Abstract excerpt

Legg-Calvé-Perthes disease (LCPD) is a rare disease caused by avascular necrosis of the femoral head. Although its etiology is still not fully understood, evidence suggests that heritable prothrombotic and inflammatory factors, as well as environmental factors, may be implicated in its onset and progress. The objective of this study is to describe the genetic, biochemical, and environmental factors that may be...

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Identifiers

PMID: 41828420
DOI: 10.3390/ijms27052195
PMCID: PMC12984531

Genes

CBS
COL1A1
COL2A1
MTHFR
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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