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Single-cell analysis identifies critical regulators of spermatogonial development and differentiation in cattle-yak bulls

19 Apr 2024

Abstract excerpt

Spermatogenesis is a continuous process in which functional sperm are produced through a series of mitotic and meiotic divisions and morphological changes in germ cells. The aberrant development and fate transitions of spermatogenic cells cause hybrid sterility in mammals. Cattle-yak, a hybrid animal between taurine cattle (Bos taurus) and yak (Bos grunniens), exhibits male-specific sterility due to spermatogenic...

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PMID: 38642661
DOI: 10.3168/jds.2023-24442

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