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Abortive Infection of Animal Cells: What Goes Wrong

17 Apr 2024

Abstract excerpt

Even if a virus successfully binds to a cell, defects in any of the downstream steps of the viral life cycle can preclude the production of infectious virus particles. Such abortive infections are likely common in nature and can provide fundamental insights into the cell and host tropism of viral pathogens. Research over the past 60 years has revealed an incredible diversity of abortive infections by DNA and RNA...

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PMID: 38631917
DOI: 10.1146/annurev-virology-100422-023037

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