Article
Attention-deficit/hyperactivity disorder and dopamine receptor D4 (DRD4) exon 3 variable number of tandem repeats (VNTR) 2-repeat allele.
Annals of human genetics - 1 Sept 2024
Baum Larry, Lee Chi Chiu, Ye Rui, Zhong Yuanxin, Hung Se Fong, Tang Chun Pan, Ho Ting Pong, Swanson James M, Moyzis Robert K, Sham Pak-Chung, Leung Patrick Wing-Leung
Abstract excerpt
To investigate the association of attention-deficit/hyperactivity disorder (ADHD) with the 48-base pair (bp) variable number of tandem repeats (VNTR) in exon 3 of the dopamine receptor D4 (DRD4) gene, we genotyped 240 ADHD patients and their parents from Hong Kong. The 4R allele was most common, followed by 2R. We examined association between the 2R allele (relative to 4R) and ADHD by Transmission Disequilibrium...
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