Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

RACGAP1 promotes lung cancer cell proliferation through the PI3K/AKT signaling pathway

15 Apr 2024

Abstract excerpt

We aimed to investigate the expression and clinic significance of Rac GTPase Activating Protein 1 (RACGAP1) in human lung adenocarcinoma (LUAD). Online database analysis revealed a significant increase in RACGAP1 mRNA expression among 26 types of tumor tissues, including LUAD tissues. Online database and tissue microarray analyses indicated that RACGAP1 expression was significantly upregulated in LUAD tissues....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lung Cancer Treatments and Mutations
Share to Microtubule and mitosis dynamics
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38622149
DOI: 10.1038/s41598-024-58539-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

RACGAP1 promotes lung cancer cell proliferation through the PI3K/AKT signaling pathwayPMID 38622149Read ↗

Assessment of RACGAP1 as a Prognostic and Immunological Biomarker in Multiple Human Tumors: A Multiomics AnalysisSemantic proximity Read ↗

RACK1 Promotes Non-small-cell Lung Cancer Tumorigenicity through Activating Sonic Hedgehog Signaling PathwaySemantic proximity Read ↗

Integrated Pan-Cancer Profiling of RAC1: Prognostic, Immunomodulatory, and Therapeutic Resistance InsightsSemantic proximity Read ↗

Single-cell RNA sequencing reveals the mechanism of PI3K/AKT/mTOR signaling pathway activation in lung adenocarcinoma by KRAS mutation.Semantic proximity Read ↗

Gene Regulation by Antitumor miR-204-5p in Pancreatic Ductal Adenocarcinoma: The Clinical Significance of Direct RACGAP1 RegulationSemantic proximity Read ↗

Long non-coding RNA MALAT1 promotes proliferation and suppresses apoptosis of glioma cells through derepressing Rap1B by sponging miR-101.Semantic proximity Read ↗

RAC1: Comprehensive Analysis of Genetic Alteration, Prognostic and Immunological Role Over Tumor ProfilesSemantic proximity Read ↗

Id1 promotes lung cancer cell proliferation and tumor growth through Akt-related pathwaySemantic proximity Read ↗

Long non-coding RNA PRKG1-AS1 Promotes Cell Proliferation and Migration in Lung AdenocarcinomaSemantic proximity Read ↗

TFAP2C-mediated upregulation of TGFBR1 promotes lung tumorigenesis and epithelial–mesenchymal transitionSemantic proximity Read ↗

RNA-seq Identification of RACGAP1 as a Metastatic Driver in Uterine CarcinosarcomaSemantic proximity Read ↗

XAF1 nonsense mutation rs117407731 enhances lung adenocarcinoma susceptibility via apoptosis suppression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.