The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis.

doi:10.1007/s00535-024-02098-8

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Article

The biochemical pattern defines MASLD phenotypes linked to distinct histology and prognosis.

Journal of gastroenterology - 1 Jul 2024

Ampuero Javier, Aller Rocío, Gallego-Durán Rocío, Crespo Javier, Calleja Jose Luis, García-Monzón Carmelo, Gómez-Camarero Judith, Caballería Joan, Lo Iacono Oreste, Ibañez Luis, García-Samaniego Javier, Albillos Agustín, Francés Rubén, Fernández-Rodríguez Conrado, Maya-Miles Douglas, Diago Moisés, Poca Maria, Andrade Raúl J, Latorre Raquel, Jorquera Francisco, Morillas Rosa María, Escudero Desamparados, Hernández-Guerra Manuel, Pareja-Megia María Jesús, Banales Jesús M, Aspichueta Patricia, Benlloch Salvador, Rosales José Miguel, Turnes Juan, Romero-Gómez Manuel

Abstract excerpt

BACKGROUND: MASLD can manifest as hepatocellular damage, which can result in mild elevation of aminotransferases. However, in some patients, MASLD presents with cholestatic pattern. OBJECTIVE: To assess the impact of the biochemical pattern on the natural course of MASLD, including liver damage in histology, the accuracy of non-invasive tests(NITs), and prognosis. METHODS: Multicenter study enrolling 2156...

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PMID: 38619600
DOI: 10.1007/s00535-024-02098-8
PMCID: PMC11217049

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